Our Mission

California Pacific CURRENTS: The online journal of CPMC Research Institute

cultured astrocytes (a type of brain neuron)

Pictured here are cultured astrocytes (a type of brain neuron) stained for the intermediate filament protein GFAP. The image was processed using the lens-flare filter in Adobe Photoshop. Courtesy of Dr. Dmitri Leonoudakis.

About Us

Research has catalyzed medical advances at California Pacific Medical Center (CPMC) for over 100 years. The California Pacific Medical Center Research Institute (CPMCRI) brings clinicians and researchers together to discover improved treatments and diagnostic technologies.

Over 80 clinical and basic science principal investigators lead innovative research in cancer, aging, arthritis, cardiovascular disease, diabetes, epilepsy, infectious diseases, drug addiction, neurobiology of pain, neurodegenerative diseases, and osteoporosis. Our clinical and translational scientists merge research institute interests with the needs of CPMC’s medical center, making research an integral foundation for improved patient care. Because of this expertise, peer institutes are learning from and partnering with our investigators in national and international studies and programs.

For example, a variety of large national cohort studies are conducted via the San Francisco Coordinating Center (SFCC), placing CPMCRI at the forefront of research into longevity and many common illnesses.

In addition, over 350 clinical trials initiated through the Office of Clinical Research offer patients access to an extensive portfolio of studies potentially suited to their particular health concerns.

Many of these initiatives and advances are made possible by grants provided by the National Institutes of Health, non-profit foundations and associations, and we are grateful for this support.

CPMC, a Sutter Health affiliate, is uniquely positioned among medical centers. As a community hospital focused on delivering compassionate patient care, many of its clinicians are also researchers, and our Research Institute publishes findings, develops novel protocols and pioneers new tests and treatments at a rate more commonly found at major universities. All of this activity fosters improved patient care, and enables CPMC to recruit and retain clinician-scientists of the highest caliber.

Facts and Figures

CPMCRI Cancer Avatar Project Facts, Stats and Achievements


Tumor types being studied in patient-derived xenograft (PDX) models


Blood and tumor specimens processed to date


PDX models screened for response to single and combination drug therapies