Head and Neck Cancer Clinical Trials

California Pacific CURRENTS: The online journal of CPMC Research Institute

Randomized Phase II/III Trial of Surgery and Postoperative Radiation Delivered With Concurrent Cisplatin Versus Docetaxel Versus Docetaxel and Cetuximab for High-Risk Squamous Cell Cancer of the Head and Neck

Description: This randomized phase II/III trial studies how well radiation therapy works when given together with cisplatin compared to docetaxel or cetuximab and docetaxel after surgery in treating patients with stage III-IV squamous cell head and neck cancer

Investigators

  • NCI - National Cancer Institute

Eligibility Requirements

Subjects, 18 y/o and older, with a pathologically (histologically or cytologically) proven diagnosis of head and neck squamous cell carcinoma (HNSCC) involving the oral cavity (excluding lips), oropharynx (p16 negative), larynx, or hypopharynx within 63 days of registration

Status

Please contact site for study status

Contacts

Peter Gasper, 415-600-3472

 

Randomized Phase II and Phase III Studies of Individualized Treatment for Nasopharyngeal Carcinoma Based on Biomarker Epstein Barr Virus (EBV) Deoxyribonucleic Acid (DNA)

Description: Individualized Treatment in Treating Patients With Stage II-IVB Nasopharyngeal Cancer Based on EBV DNA

Investigators

  • NCI - National Cancer Institute

Eligibility Requirements

Subjects, 18 y/o and older, with a biopsy proven (from primary lesion and/or lymph nodes) diagnosis of cancer of the nasopharynx

Status

Please contact site for study status

Contacts

Peter Gasper, 415-600-3472

 

A Phase III Study of Postoperative Radiation Therapy (IMRT) +/- Cetuximab for Locally-Advanced Resected Head and Neck Cancer

Description: This randomized phase III trial is studying radiation therapy to see how well it works compared with radiation therapy given together with cetuximab in treating patients who have undergone surgery for locally advanced head and neck cancer

Investigators

  • NCI - National Cancer Institute

Eligibility Requirements

Subjects, 18 y/o and older, with a histologically confirmed squamous cell carcinoma (including variants, such as verrucous carcinoma, spindle cell carcinoma, or carcinoma not otherwise specified) of the head and neck

Status

Please contact site for study status

Contacts

Peter Gasper, 415-600-3472